The use of Collatamp G, local gentamicin-collagen sponge, in reducing wound infection

Int Surg. 2014 Sep-Oct;99(5):565-70. doi: 10.9738/INTSURG-D-13-00171.1.

Abstract

We conducted a retrospective study to examine the role of Collatamp G in reducing postoperative surgical site infection (SSI) in patients with different wound classes. Ninety-two patients (62 men and 30 women; mean age, 58 years; range, 29-88 years) who had undergone surgery between December 2009 and November 2011 in Tan Tock Seng Hospital and who had application of Collatamp G in their wound before closure were included in the study. The primary endpoint was the development of any superficial wound infection within 1 month postoperatively. Of 92 patients studied, 9 (10%) developed a superficial wound infection. Two of 43 patients with clean-contaminated wounds (5%), 2 of 19 with contaminated wounds (11%), and 5 of 30 with dirty-infected wounds (16%) developed infection. Use of the larger size Collatamp G (10 × 10 cm) also appears to have a lower incidence of SSI compared with the smaller Collatamp G (5 × 5 cm); 4% and 12%, respectively. Our data suggest that postoperative SSI was reduced in the group of patients with dirty-infected wound class. SSI appears to be decreased with use of the larger size Collatamp G.

Keywords: Collatamp G; Dirty infected; Gentamicin-collagen; Surgical site infection; Wound class.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Animals
  • Collagen*
  • Drug Delivery Systems*
  • Female
  • Gentamicins / administration & dosage*
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Surgical Wound Infection / prevention & control*

Substances

  • Gentamicins
  • Collagen