Probing astroglia with carbon nanotubes: modulation of form and function

Philos Trans R Soc Lond B Biol Sci. 2014 Oct 19;369(1654):20130598. doi: 10.1098/rstb.2013.0598.

Abstract

Carbon nanotubes (CNTs) have shown much promise in neurobiology and biomedicine. Their structural stability and ease of chemical modification make them compatible for biological applications. In this review, we discuss the effects that chemically functionalized CNTs, applied as colloidal solutes or used as strata, have on the morpho-functional properties of astrocytes, the most abundant cells present in the brain, with an insight into the potential use of CNTs in neural prostheses.

Keywords: astrocytes; carbon nanotubes; glial fibrillary acidic protein; graft copolymers; morphology; proliferation.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Astrocytes / metabolism*
  • Biocompatible Materials / chemistry*
  • Biocompatible Materials / metabolism
  • Colloids / chemistry*
  • Graphite / chemistry
  • Humans
  • Nanotubes, Carbon / chemistry*
  • Tissue Scaffolds / chemistry*

Substances

  • Biocompatible Materials
  • Colloids
  • Nanotubes, Carbon
  • Graphite