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Host factors for retroviral integration site selection.
Trends Biochem Sci. 2015 Feb;40(2):108-16. doi: 10.1016/j.tibs.2014.12.001. Epub 2014 Dec 31.
Trends Biochem Sci. 2015.
PMID: 25555456
Review.
Small-molecule inhibitors of the LEDGF/p75 binding site of integrase block HIV replication and modulate integrase multimerization.
Christ F, Shaw S, Demeulemeester J, Desimmie BA, Marchand A, Butler S, Smets W, Chaltin P, Westby M, Debyser Z, Pickford C.
Christ F, et al.
Antimicrob Agents Chemother. 2012 Aug;56(8):4365-74. doi: 10.1128/AAC.00717-12. Epub 2012 Jun 4.
Antimicrob Agents Chemother. 2012.
PMID: 22664975
Free PMC article.
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Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors.
Kessl JJ, Jena N, Koh Y, Taskent-Sezgin H, Slaughter A, Feng L, de Silva S, Wu L, Le Grice SF, Engelman A, Fuchs JR, Kvaratskhelia M.
Kessl JJ, et al.
J Biol Chem. 2012 May 11;287(20):16801-11. doi: 10.1074/jbc.M112.354373. Epub 2012 Mar 21.
J Biol Chem. 2012.
PMID: 22437836
Free PMC article.
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Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication.
Christ F, Voet A, Marchand A, Nicolet S, Desimmie BA, Marchand D, Bardiot D, Van der Veken NJ, Van Remoortel B, Strelkov SV, De Maeyer M, Chaltin P, Debyser Z.
Christ F, et al.
Nat Chem Biol. 2010 Jun;6(6):442-8. doi: 10.1038/nchembio.370. Epub 2010 May 16.
Nat Chem Biol. 2010.
PMID: 20473303
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