Draft Genome Sequence of a New Delhi Metallo-β-Lactamase-5 (NDM-5)-Producing Multidrug-Resistant Escherichia coli Isolate

Tom J B de Man; K Allison Perry; Johannetsy J Avillan; J Kamile Rasheed; Brandi M Limbago

doi:10.1128/genomeA.00017-15

Draft Genome Sequence of a New Delhi Metallo-β-Lactamase-5 (NDM-5)-Producing Multidrug-Resistant Escherichia coli Isolate

Genome Announc. 2015 Mar 5;3(2):e00017-15. doi: 10.1128/genomeA.00017-15.

Authors

Tom J B de Man¹, K Allison Perry², Johannetsy J Avillan², J Kamile Rasheed², Brandi M Limbago²

Affiliations

¹ Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA xku6@cdc.gov.
² Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Abstract

A multidrug-resistant Escherichia coli isolate from an abdominal lesion displayed resistance to all β-lactams tested, including carbapenems, in addition to macrolides, fluoroquinolones, and tetracycline. Sequence analyses demonstrated the presence of blaNDM-5 in addition to at least 13 genes and 6 efflux pumps associated with antibiotic resistance.