The prevalence of malaria among HIV seropositive individuals and the impact of the co- infection on their hemoglobin levels

Ann Clin Microbiol Antimicrob. 2015 Mar 7:14:10. doi: 10.1186/s12941-015-0064-6.

Abstract

Background: Malaria and HIV/AIDS are the two most common infections in sub-Sahara Africa. There are hypotheses and study reports on the possible association between these two infections, hence the prevalence and outcome of their co-infection in an endemic population will be important in defining healthcare strategies. A cross sectional study was carried out at the Holy Family Hospital in Techiman, Ghana, between November 2011 and January 2012, to determine the prevalence of malaria among HIV sero-positive patients and its impact on hemoglobin levels.

Method: A total of 400 HIV sero-positive participants (292 females and 108 males) aged between 1 and 73 years were randomly sampled for the study. A questionnaire was administered and 2 ml of venous blood samples were drawn for malaria parasites detection, CD4 count and haemoglobin level estimations.

Results: Malaria parasites were detected in 47 (11.75%) of the participants. There was no statistically significant difference between the malaria prevalence rate of females (12.1%) and males (10.2%) P = 0.6047. An overall anaemia prevalence of 67% was observed. Among participants with malaria the anaemia prevalence was 93.6%. The CD4 cell count of all the participants ranged between 3 and 1604 cells/μl with a mean of 386.2 (±274.3) cells/μl. Participants with malaria had CD4 cell count ranged 3 and 512 Cells/μl with the mean being 186.33 (±133.49) Cells/μl. Out of 377 participants (all above 15 years) interviewed on knowledge of malaria transmission and prevention, 87.0% had knowledge on transmission but only 8.5% use in bed nets.

Conclusion: It was revealed that almost all the patients with malaria infection were anemic.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • CD4 Lymphocyte Count
  • Child
  • Child, Preschool
  • Coinfection / blood*
  • Coinfection / epidemiology
  • Coinfection / physiopathology
  • Cross-Sectional Studies
  • Female
  • Ghana / epidemiology
  • HIV Antibodies / blood
  • HIV Seropositivity / blood*
  • HIV Seropositivity / epidemiology
  • HIV Seropositivity / physiopathology
  • Hemoglobins / analysis*
  • Humans
  • Infant
  • Malaria / blood*
  • Malaria / epidemiology
  • Malaria / physiopathology
  • Male
  • Middle Aged
  • Prevalence
  • Young Adult

Substances

  • HIV Antibodies
  • Hemoglobins