25908823,27671644,28334607,31128467,31439792,31439793,32049506,32828421,33053563[uid] - Search Results

Year	Number of Results
2015	1
2016	1
2017	1
2019	3
2020	3
2024	0

1

SARM1 activation triggers axon degeneration locally via NAD⁺ destruction.

Gerdts J, Brace EJ, Sasaki Y, DiAntonio A, Milbrandt J. Gerdts J, et al. Science. 2015 Apr 24;348(6233):453-7. doi: 10.1126/science.1258366. Epub 2015 Apr 23. Science. 2015. PMID: 25908823 Free PMC article.

2

SARM1-specific motifs in the TIR domain enable NAD+ loss and regulate injury-induced SARM1 activation.

Summers DW, Gibson DA, DiAntonio A, Milbrandt J. Summers DW, et al. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6271-E6280. doi: 10.1073/pnas.1601506113. Epub 2016 Sep 26. Proc Natl Acad Sci U S A. 2016. PMID: 27671644 Free PMC article.

3

The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD⁺ Cleavage Activity that Promotes Pathological Axonal Degeneration.

Essuman K, Summers DW, Sasaki Y, Mao X, DiAntonio A, Milbrandt J. Essuman K, et al. Neuron. 2017 Mar 22;93(6):1334-1343.e5. doi: 10.1016/j.neuron.2017.02.022. Neuron. 2017. PMID: 28334607 Free PMC article.

4

A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death.

Zhao ZY, Xie XJ, Li WH, Liu J, Chen Z, Zhang B, Li T, Li SL, Lu JG, Zhang L, Zhang LH, Xu Z, Lee HC, Zhao YJ. Zhao ZY, et al. iScience. 2019 May 31;15:452-466. doi: 10.1016/j.isci.2019.05.001. Epub 2019 May 4. iScience. 2019. PMID: 31128467 Free PMC article.

5

NAD⁺ cleavage activity by animal and plant TIR domains in cell death pathways.

Horsefield S, Burdett H, Zhang X, Manik MK, Shi Y, Chen J, Qi T, Gilley J, Lai JS, Rank MX, Casey LW, Gu W, Ericsson DJ, Foley G, Hughes RO, Bosanac T, von Itzstein M, Rathjen JP, Nanson JD, Boden M, Dry IB, Williams SJ, Staskawicz BJ, Coleman MP, Ve T, Dodds PN, Kobe B. Horsefield S, et al. Science. 2019 Aug 23;365(6455):793-799. doi: 10.1126/science.aax1911. Science. 2019. PMID: 31439792

6

TIR domains of plant immune receptors are NAD⁺-cleaving enzymes that promote cell death.

Wan L, Essuman K, Anderson RG, Sasaki Y, Monteiro F, Chung EH, Osborne Nishimura E, DiAntonio A, Milbrandt J, Dangl JL, Nishimura MT. Wan L, et al. Science. 2019 Aug 23;365(6455):799-803. doi: 10.1126/science.aax1771. Science. 2019. PMID: 31439793 Free PMC article.

7

Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1.

Loring HS, Icso JD, Nemmara VV, Thompson PR. Loring HS, et al. Biochemistry. 2020 Mar 3;59(8):933-942. doi: 10.1021/acs.biochem.9b01078. Epub 2020 Feb 17. Biochemistry. 2020. PMID: 32049506 Free PMC article.

8

Identification of the first noncompetitive SARM1 inhibitors.

Loring HS, Parelkar SS, Mondal S, Thompson PR. Loring HS, et al. Bioorg Med Chem. 2020 Sep 15;28(18):115644. doi: 10.1016/j.bmc.2020.115644. Epub 2020 Jul 17. Bioorg Med Chem. 2020. PMID: 32828421 Free PMC article.

9

The NAD⁺-mediated self-inhibition mechanism of pro-neurodegenerative SARM1.

Jiang Y, Liu T, Lee CH, Chang Q, Yang J, Zhang Z. Jiang Y, et al. Nature. 2020 Dec;588(7839):658-663. doi: 10.1038/s41586-020-2862-z. Epub 2020 Oct 14. Nature. 2020. PMID: 33053563

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

9 results

Results by year

Search Page

Filters

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

Search Results

9 results

Results by year