Should thiopurine methyltransferase (TPMT) activity be determined before prescribing azathioprine, mercaptopurine, or thioguanine?

Cleve Clin J Med. 2015 Jul;82(7):409-13. doi: 10.3949/ccjm.82a.14106.

Jennifer DiPiero¹, Kathryn Teng^{2

3}, J Kevin Hicks^{4

5}

¹ Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.
² Director, Internal Medicine and Community Medicine, MetroHealth Medical Center, Cleveland, OH, USA.
³ Assistant Professor, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
⁴ Director, Personalized Medication Program, Department of Pharmacy, Genomic Medicine Institute, Cleveland Clinic, Cleveland, OH, USA. E-mail: hicksj4@ccf.org.
⁵ Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.

No abstract available

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