Abstract
A 55-year-old man with well-controlled HIV had severe diarrhea for 3 weeks and developed multiorgan dysfunction and bacteremia due to Escherichia coli. The genome of the patient's isolate had features characteristic of extraintestinal pathogenic E. coli and genes distantly related to those defining enteropathogenic E. coli.
Keywords:
case report; comparative genomics; hemolysin; type 3 secretion; virulence factors.
© FEMS 2015.
Publication types
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Case Reports
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Research Support, N.I.H., Extramural
MeSH terms
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Bacteremia / complications
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Bacteremia / microbiology*
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Bacteremia / pathology
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DNA, Bacterial / chemistry
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DNA, Bacterial / genetics
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Diarrhea / complications
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Diarrhea / microbiology*
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Diarrhea / pathology
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Enteropathogenic Escherichia coli / classification
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Enteropathogenic Escherichia coli / genetics
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Enteropathogenic Escherichia coli / isolation & purification*
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Escherichia coli Infections / microbiology*
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Escherichia coli Infections / pathology
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Genes, Bacterial
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Genome, Bacterial
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HIV Infections / complications
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Humans
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Male
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Middle Aged
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Molecular Sequence Data
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Multiple Organ Failure / microbiology*
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Multiple Organ Failure / pathology
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Sequence Analysis, DNA