Therapeutic potential of dairy bioactive peptides: A contemporary perspective

Crit Rev Food Sci Nutr. 2018 Jan 2;58(1):105-115. doi: 10.1080/10408398.2015.1136590. Epub 2017 Jun 28.

Abstract

Dairy products are associated with numerous health benefits. These are a good source of nutrients such as carbohydrates, protein (bioactive peptides), lipids, minerals, and vitamins, which are essential for growth, development, and maintenance of the human body. Accordingly, dairy bioactive peptides are one of the targeted compounds present in different dairy products. Dairy bioactive compounds can be classified as antihypertensive, anti-oxidative, immmunomodulant, anti-mutagenic, antimicrobial, opoid, anti-thrombotic, anti-obesity, and mineral-binding agents, depending upon biological functions. These bioactive peptides can easily be produced by enzymatic hydrolysis, and during fermentation and gastrointestinal digestion. For this reason, fermented dairy products, such as yogurt, cheese, and sour milk, are gaining popularity worldwide, and are considered excellent source of dairy peptides. Furthermore, fermented and non-fermented dairy products are associated with lower risks of hypertension, coagulopathy, stroke, and cancer insurgences. The current review article is an attempt to disseminate general information about dairy peptides and their health claims to scientists, allied stakeholders, and, certainly, readers.

Keywords: Bioactive peptides; dairy nutrition; dairy peptides; food; health.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Angiotensin-Converting Enzyme Inhibitors
  • Anti-Infective Agents
  • Antihypertensive Agents
  • Antimutagenic Agents
  • Antioxidants
  • Dairy Products / analysis*
  • Digestion
  • Fermentation
  • Food Handling
  • Health Promotion*
  • Humans
  • Immunologic Factors
  • Intestinal Absorption
  • Milk Proteins / chemistry
  • Peptide Fragments / chemistry
  • Peptide Fragments / metabolism
  • Peptide Fragments / therapeutic use*

Substances

  • Angiotensin-Converting Enzyme Inhibitors
  • Anti-Infective Agents
  • Antihypertensive Agents
  • Antimutagenic Agents
  • Antioxidants
  • Immunologic Factors
  • Milk Proteins
  • Peptide Fragments