Relationship between periodontal disease and asthma among overweight/obese adults

J Clin Periodontol. 2016 Jul;43(7):566-71. doi: 10.1111/jcpe.12553. Epub 2016 May 19.

Abstract

Aim: To assess the relationship between oral health and asthma.

Methods: Data from 1315 overweight or obese individuals, aged 40-65 years were used. Asthma was self-reported, whereas periodontitis, bleeding on probing (BOP) and plaque index were determined by clinical examinations.

Results: Using logistic regression adjusting for gender, smoking status, age, body mass index, family history of asthma and income level, revealed that the odds ratio (OR) of asthma for a participant with severe periodontitis was 0.44 (95% confidence interval: 0.27, 0.70) that of a participant with none/mild periodontitis. On the other hand, proportion of BOP sites and plaque index were not statistically significant. For a participant with severe periodontitis, the OR of taking asthma medication was 0.20 (95% confidence interval: 0.09, 0.43) that of a participant with none/mild periodontitis. Moreover, proportion of BOP sites was statistically associated with use of asthma medication, whereas plaque index still remained non-significant.

Conclusion: Participants with severe periodontitis were less likely to have asthma. Stronger evidence of an inverse association was found when using asthma medication as outcome.

Keywords: asthma; asthma medication; hygiene hypothesis; periodontal disease; periodontitis.

MeSH terms

  • Aged
  • Asthma*
  • Dental Plaque Index
  • Humans
  • Middle Aged
  • Obesity
  • Overweight
  • Periodontal Attachment Loss
  • Periodontal Index