Abstract
The conversion of fibrinogen to fibrin is a process that has long fascinated an army of researchers. In this brief review some early break-through observations are noted and a few later unexpected results described.
Keywords:
Factor XIII; Fibrin; Fibrinogen; Papain; Protofibrinogen; Thrombin.
Copyright © 2016 Elsevier B.V. All rights reserved.
Publication types
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Historical Article
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Review
MeSH terms
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Animals
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Blood Coagulation / physiology*
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Ciona intestinalis / chemistry
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Ciona intestinalis / physiology
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Factor XIII / chemistry
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Factor XIII / history
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Factor XIII / metabolism*
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Fibrin / chemistry
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Fibrin / history
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Fibrin / metabolism*
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Fibrinogen / chemistry
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Fibrinogen / history
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Fibrinogen / metabolism*
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History, 20th Century
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History, 21st Century
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Humans
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Models, Molecular
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Phase Transition
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Proteolysis
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Static Electricity
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Thrombin / chemistry
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Thrombin / history
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Thrombin / metabolism*
Substances
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Fibrin
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Fibrinogen
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Factor XIII
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Thrombin