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Matrix Biol. 2017 Jul;60-61:5-7. doi: 10.1016/j.matbio.2016.08.002. Epub 2016 Aug 9.

The conversion of fibrinogen to fibrin: A brief history of some key events.

Author information

1
Department of Chemistry & Biochemistry, University of California, San Diego, La Jolla, CA 92093-0314, USA; Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093-0314, USA. Electronic address: rdoolittle@ucsd.edu.

Abstract

The conversion of fibrinogen to fibrin is a process that has long fascinated an army of researchers. In this brief review some early break-through observations are noted and a few later unexpected results described.

KEYWORDS:

Factor XIII; Fibrin; Fibrinogen; Papain; Protofibrinogen; Thrombin

PMID:
27519977
DOI:
10.1016/j.matbio.2016.08.002
[Indexed for MEDLINE]

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