Prostate-Specific Membrane Antigen Uptake in Small Cleaved B-Cell Follicular Non-Hodgkin Lymphoma

Clin Nucl Med. 2016 Dec;41(12):980-981. doi: 10.1097/RLU.0000000000001378.

Abstract

A 68-year-old man with treated prostate cancer 3 years earlier and small cleaved B-cell follicular lymphoma diagnosed 1 year prior and monitored clinically with no active intervention ("watch and wait" approach) was referred for Ga-prostate-specific membrane antigen (PSMA) PET/CT with rising prostate-specific antigen level. PET/CT demonstrated diffuse PSMA uptake in the prostate (SUVmax 3.6) and multiple PSMA-avid nonenlarged lymph nodes. Moderate PSMA uptake (SUVmax 4.7) was also noted in an enlarged right inguinal lymph node (SUVmax 4.7), which on core biopsy confirmed small cleaved B-cell follicular lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biomarkers, Tumor / metabolism*
  • Humans
  • Lymphoma, Follicular / diagnostic imaging*
  • Male
  • Positron Emission Tomography Computed Tomography / methods*
  • Prostate-Specific Antigen / metabolism*
  • Prostatic Neoplasms / diagnostic imaging*
  • Prostatic Neoplasms / metabolism

Substances

  • Biomarkers, Tumor
  • Prostate-Specific Antigen