Abstract
The mechanisms of action of polyphenols have attracted much attention. Catechins are generally known as tea polyphenols. Researchers have extensively investigated the molecular mechanisms of these substances, especially (-)-epigallocatechin gallate of green tea catechin, and have provided new insights in the prevention and therapy for chronic diseases. This chapter summarizes catechins and their effects on chronic diseases, including metabolic syndromes, cardiovascular diseases, neurodegenerative diseases, and cancer, focusing on the effects of green tea catechins.
Keywords:
Cancer; Cardiovascular disease; Catechin; Chemoprevention; Green tea; Metabolic syndrome; Neurodegenerative disease; Obesity.
MeSH terms
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Animals
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification
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Antineoplastic Agents, Phytogenic / therapeutic use*
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Cardiovascular Agents / chemistry
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Cardiovascular Agents / isolation & purification
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Cardiovascular Agents / therapeutic use*
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Catechin / chemistry
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Catechin / isolation & purification
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Catechin / therapeutic use*
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Chronic Disease / drug therapy*
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Disease Models, Animal
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Drug Discovery / methods*
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Humans
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Molecular Structure
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Neuroprotective Agents / chemistry
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Neuroprotective Agents / isolation & purification
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Neuroprotective Agents / therapeutic use*
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Phytotherapy
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Plant Extracts / chemistry
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Plant Extracts / isolation & purification
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Plant Extracts / therapeutic use*
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Plants, Medicinal
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Signal Transduction / drug effects
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Structure-Activity Relationship
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Tea / chemistry*
Substances
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Antineoplastic Agents, Phytogenic
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Cardiovascular Agents
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Neuroprotective Agents
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Plant Extracts
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Tea
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Catechin