Application of Fused Deposition Modelling (FDM) Method of 3D Printing in Drug Delivery

Curr Pharm Des. 2017;23(3):433-439. doi: 10.2174/1381612822666161026162707.

Abstract

Three-dimensional (3D) printing is an emerging manufacturing technology for biomedical and pharmaceutical applications. Fused deposition modelling (FDM) is a low cost extrusion-based 3D printing technique that can deposit materials layer-by-layer to create solid geometries. This review article aims to provide an overview of FDM based 3D printing application in developing new drug delivery systems. The principle methodology, suitable polymers and important parameters in FDM technology and its applications in fabrication of personalised tablets and drug delivery devices are discussed in this review. FDM based 3D printing is a novel and versatile manufacturing technique for creating customised drug delivery devices that contain accurate dose of medicine( s) and provide controlled drug released profiles.

Keywords: 3D printing; Drug delivery; FDM; Polymers.

Publication types

  • Review

MeSH terms

  • Computer-Aided Design
  • Drug Delivery Systems* / instrumentation
  • Printing, Three-Dimensional* / instrumentation
  • Technology, Pharmaceutical* / instrumentation