TheCellMap.org: A Web-Accessible Database for Visualizing and Mining the Global Yeast Genetic Interaction Network

G3 (Bethesda). 2017 May 5;7(5):1539-1549. doi: 10.1534/g3.117.040220.

Abstract

Providing access to quantitative genomic data is key to ensure large-scale data validation and promote new discoveries. TheCellMap.org serves as a central repository for storing and analyzing quantitative genetic interaction data produced by genome-scale Synthetic Genetic Array (SGA) experiments with the budding yeast Saccharomyces cerevisiae In particular, TheCellMap.org allows users to easily access, visualize, explore, and functionally annotate genetic interactions, or to extract and reorganize subnetworks, using data-driven network layouts in an intuitive and interactive manner.

Keywords: genetic interactions; genetic network; synthetic genetic array SGA; yeast genetics.

MeSH terms

  • Protein Binding
  • Protein Interaction Maps*
  • Proteome / metabolism
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae / metabolism
  • Saccharomyces cerevisiae Proteins / genetics
  • Saccharomyces cerevisiae Proteins / metabolism*
  • Software*

Substances

  • Proteome
  • Saccharomyces cerevisiae Proteins