Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease

Mucosal Immunol. 2017 May;10(3):829. doi: 10.1038/mi.2017.29.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Epithelial Sodium Channels / genetics
  • Epithelial Sodium Channels / metabolism*
  • Humans
  • Lung / pathology*
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Mucin 5AC / genetics
  • Mucin 5AC / metabolism*
  • Mucin-5B / genetics
  • Mucin-5B / metabolism*
  • Mucociliary Clearance
  • Mucus / metabolism*
  • Pulmonary Disease, Chronic Obstructive / immunology*

Substances

  • Epithelial Sodium Channels
  • MUC5AC protein, human
  • MUC5B protein, human
  • Mucin 5AC
  • Mucin-5B
  • Scnn1b protein, mouse