Lignins and Their Derivatives with Beneficial Effects on Human Health

Int J Mol Sci. 2017 Jun 7;18(6):1219. doi: 10.3390/ijms18061219.

Abstract

A review of the pharmacological applications of lignins provides evidence of their protective role against the development of different diseases. In many cases, the effects of lignins could be explained by their antioxidant capacity. Here, we present a systematic review of the literature from the period 2010-2016 which provides information concerning new applications of lignins derived from recent research. The most promising findings are reported, including the methodologies employed and results obtained with lignins or their derivatives which may improve human health. We highlight potential applications in the treatment of obesity, diabetes, thrombosis, viral infections and cancer. Moreover, we report both that lignins can be used in the preparation of nanoparticles to deliver different drugs and also their use in photoprotection.

Keywords: antioxidant capacity; antiviral effect; applicability; human health; lignin.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Animals
  • Antioxidants / pharmacology
  • Antioxidants / therapeutic use
  • Antiviral Agents / pharmacology
  • Antiviral Agents / therapeutic use
  • Drug Delivery Systems
  • Health Promotion*
  • Humans
  • Immunologic Factors / pharmacology
  • Immunologic Factors / therapeutic use
  • Lignin / analogs & derivatives
  • Lignin / pharmacology*
  • Lignin / therapeutic use

Substances

  • Antioxidants
  • Antiviral Agents
  • Immunologic Factors
  • Lignin