Prevention of Central Line-Associated Bloodstream Infections

Infect Dis Clin North Am. 2017 Sep;31(3):551-559. doi: 10.1016/j.idc.2017.05.007. Epub 2017 Jul 5.

Abstract

Central venous catheters (CVCs) are commonly used in critically ill patients and offer several advantages to peripheral intravenous access. However, indwelling CVCs have the potential to lead to bloodstream infections, with the risk increasing with an array of characteristics, such as catheter choice, catheter location, insertion technique, and catheter maintenance. Evidence-based guidelines have led to a significant reduction in the incidence of bloodstream infections associated with CVCs. The combination of guideline implementation and newer technologies has the potential to further reduce morbidity and mortality from infections related to CVCs.

Keywords: Blood stream infection; CLABSI; CRBSI; Central line; Central venous catheter.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Bacteremia / drug therapy
  • Bacteremia / microbiology
  • Bacteremia / prevention & control*
  • Catheter-Related Infections / drug therapy
  • Catheter-Related Infections / microbiology
  • Catheter-Related Infections / prevention & control*
  • Catheterization, Central Venous / adverse effects*
  • Catheters, Indwelling / adverse effects
  • Central Venous Catheters / adverse effects
  • Central Venous Catheters / microbiology*
  • Cross Infection / microbiology
  • Cross Infection / prevention & control*
  • Humans
  • Incidence
  • Intensive Care Units