A Comprehensive Review on Role of Nanoparticles in Therapeutic Delivery of Medicine

Pharm Nanotechnol. 2017;5(4):263-275. doi: 10.2174/2211738505666171113130639.

Abstract

Background: The effective targeted drug delivery system is significant for future development of medicinal product and healthcare. There are also different types of nanostructures which include solid lipid nanoparticles, liposomes, dendrimers, nanostructured lipid carriers, lipid drug conjugate, liquid crystalline particles, polymeric nanocrystals, polymeric nanoparticles and superparamagnetic nanoparticles which have been considered as advanced carriers in drug delivery system. Method & Discussion: In this regard, nano carriers are bringing revolution in therapeutic delivery of drug as compared to conventional delivery systems by overcoming the limitations of usual methods.

Conclusion: The objective of this review is to cover the drug delivery system of various therapeutic drugs and biomolecules by means of polymeric nanoparticles, dendrimers, liposomal nanoparticles and magnetic nanoparticles by describing the methods of formulation development.

Keywords: Biomolecules; drug delivery system; healthcare; medicine; nanoparticles; polymeric.

Publication types

  • Review

MeSH terms

  • Chemistry, Pharmaceutical / methods
  • Delayed-Action Preparations / administration & dosage
  • Delayed-Action Preparations / chemistry
  • Dendrimers / chemistry
  • Drug Carriers / chemistry*
  • Humans
  • Lipids / chemistry
  • Liposomes / chemistry
  • Nanoparticles / chemistry*
  • Polymers / chemistry

Substances

  • Delayed-Action Preparations
  • Dendrimers
  • Drug Carriers
  • Lipids
  • Liposomes
  • Polymers