Two dimensional semiconductors for ultrasound-mediated cancer therapy: the case of black phosphorus nanosheets

Jiang Ouyang; Liu Deng; Wansong Chen; Jianping Sheng; Zhenjun Liu; Liqiang Wang; You-Nian Liu

doi:10.1039/c8cc00392k

Two dimensional semiconductors for ultrasound-mediated cancer therapy: the case of black phosphorus nanosheets

Chem Commun (Camb). 2018 Mar 15;54(23):2874-2877. doi: 10.1039/c8cc00392k.

Authors

Jiang Ouyang¹, Liu Deng, Wansong Chen, Jianping Sheng, Zhenjun Liu, Liqiang Wang, You-Nian Liu

Affiliation

¹ College of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan 410083, P. R. China. chenws@csu.edu.cn liuyounian@csu.edu.cn.

PMID: 29493688
DOI: 10.1039/c8cc00392k

Abstract

With black phosphorus (BP) as an example, the first two-dimensional (2D) semiconductor based sonosensitizer (Au@BP nanohybrids) was fabricated. Under ultrasound irradiation, Au@BP nanohybrids can generate ¹O₂ in deep tissues and eradicate tumors with high efficacy. This platform paves the way for the application of 2D semiconductors in sonodynamic cancer therapy.