Causes of low peak bone mass in women

Chee Kian Chew; Bart L Clarke

doi:10.1016/j.maturitas.2017.12.010

Causes of low peak bone mass in women

Maturitas. 2018 May:111:61-68. doi: 10.1016/j.maturitas.2017.12.010. Epub 2017 Dec 15.

Authors

Chee Kian Chew¹, Bart L Clarke²

Affiliations

¹ Mayo Clinic E18-A, 200 1st Street SW, Rochester, MN, 55905, USA.
² Mayo Clinic E18-A, 200 1st Street SW, Rochester, MN, 55905, USA. Electronic address: clarke.bart@mayo.edu.

PMID: 29673833
DOI: 10.1016/j.maturitas.2017.12.010

Abstract

Peak bone mass is the maximum bone mass that accrues during growth and development. Consolidation of peak bone mass normally occurs during early adulthood. Low peak bone mass results from failure to achieve peak bone mass genetic potential, primarily due to bone loss caused by a variety of conditions or processes occurring at younger ages than usual. Recognized causes of low peak bone mass include genetic causes, endocrine disorders, nutritional disorders, chronic diseases of childhood or adolescence, medications, and idiopathic factors.

Keywords: Fractures; Osteopenia; Osteoporosis; Peak bone mass; Premenopausal status.

Publication types

Review

MeSH terms

Bone Density* / genetics
Bone and Bones / pathology*
Bone and Bones / physiopathology*
Drug-Related Side Effects and Adverse Reactions / complications
Drug-Related Side Effects and Adverse Reactions / physiopathology
Endocrine System Diseases / complications*
Endocrine System Diseases / physiopathology
Female
Humans
Nutrition Disorders / complications*
Nutrition Disorders / physiopathology
Organ Size
Osteoporosis / etiology*
Osteoporosis / genetics