Prevalence of hypoalbuminemia in outpatients with HIV/AIDS

Rev Soc Bras Med Trop. 2018 Mar-Apr;51(2):203-206. doi: 10.1590/0037-8682-0093-2017.

Abstract

Introduction: Hypoalbuminemia may predict progression of disease and mortality in patients with human immunodeficiency virus (HIV) infection/acquired immune deficiency syndrome (AIDS). This study was conducted to investigate the risk factors associated with hypoalbuminemia in outpatients with HIV/AIDS.

Methods: A cross-sectional study was performed in 196 outpatients with HIV/AIDS.

Results: The prevalence of hypoalbuminemia was 11.7%. The only risk factor associated with hypoalbuminemia was current antiretroviral therapy (no exposure: odds ratio=3.46, 95% confidence interval=1.20-10.02).

Conclusions: The monitoring of plasma albumin is key to determine when antiretroviral therapy should be initiated in individuals not exposed to antiretroviral medicines.

MeSH terms

  • Acquired Immunodeficiency Syndrome / blood
  • Acquired Immunodeficiency Syndrome / complications*
  • Acquired Immunodeficiency Syndrome / drug therapy
  • Adult
  • Anti-Retroviral Agents / administration & dosage*
  • Anti-Retroviral Agents / adverse effects
  • Cross-Sectional Studies
  • Disease Progression
  • Female
  • Humans
  • Hypoalbuminemia / blood
  • Hypoalbuminemia / epidemiology
  • Hypoalbuminemia / etiology*
  • Male
  • Middle Aged
  • Outpatients
  • Predictive Value of Tests
  • Prevalence
  • Risk Factors

Substances

  • Anti-Retroviral Agents