Nucleotide sequence analysis of a gene encoding a streptomycin/spectinomycin adenylyltransferase

Plasmid. 1985 Jan;13(1):17-30. doi: 10.1016/0147-619x(85)90052-6.

Abstract

The nucleotide sequence of 1400 bp from R-plasmid R538-1 containing the streptomycin/spectinomycin adenyltransferase gene (aadA) was determined, and the location of the aadA gene was identified by a combination of insertion and deletion mutants. Its gene product, aminoglycoside 3"-adenylyltransferase (AAD(3")(9), has a Mr of 31,600.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Bacterial Proteins / genetics*
  • Base Sequence
  • Codon / genetics
  • DNA, Bacterial / genetics
  • Escherichia coli / enzymology
  • Escherichia coli / genetics*
  • Genes
  • Genes, Bacterial*
  • Nucleotidyltransferases / genetics*
  • R Factors*

Substances

  • Bacterial Proteins
  • Codon
  • DNA, Bacterial
  • Nucleotidyltransferases
  • streptomycin-spectinomycin adenylyltransferase

Associated data

  • GENBANK/M10241