Ocular manifestations of emerging arboviruses: Dengue fever, Chikungunya, Zika virus, West Nile virus, and yellow fever

J Fr Ophtalmol. 2018 Jun;41(6):e235-e243. doi: 10.1016/j.jfo.2018.05.002. Epub 2018 Jun 19.

Abstract

Arboviruses are viral diseases transmitted by mosquitoes and tick bites. They are a major cause of morbidity and sometimes mortality. Their expansion is constant and due in part to climate change and globalization. Mostly found in tropical regions, arboviruses are sometimes the source of epidemics in Europe. Recently, the Chikungunya virus and the Zika virus were responsible for very large epidemics impacting populations that had never been in contact with those viruses. There are currently no effective antiviral treatments or vaccines. Ocular manifestations due to those infections are thus more frequent and increasingly better described. They are sometimes, as with Zika, complicated by a congenital ocular syndrome. The goal of this review is to describe the ophthalmological manifestations of Dengue fever, Chikungunya virus, Zika virus, West Nile virus, and yellow fever.

Keywords: Arboviruses; Chikungunya virus; Choroiditis; Dengue fever; Eye; Maculopathy; Neuroretinitis; Optic neuritis; Retinal vasculitis; Retinopathy; Uveitis; West Nile virus; Yellow fever; Zika virus.

Publication types

  • Review

MeSH terms

  • Arbovirus Infections* / diagnosis
  • Arbovirus Infections* / epidemiology
  • Arbovirus Infections* / virology
  • Arboviruses / classification
  • Arboviruses / isolation & purification
  • Chikungunya Fever / complications
  • Chikungunya Fever / diagnosis
  • Chikungunya Fever / epidemiology
  • Chikungunya virus / isolation & purification
  • Chikungunya virus / physiology
  • Communicable Diseases, Emerging / diagnosis
  • Communicable Diseases, Emerging / epidemiology
  • Communicable Diseases, Emerging / virology
  • Dengue / complications
  • Dengue / diagnosis
  • Dengue / epidemiology
  • Eye Infections, Viral / diagnosis
  • Eye Infections, Viral / epidemiology*
  • Eye Infections, Viral / virology*
  • Humans
  • West Nile virus / isolation & purification
  • West Nile virus / physiology
  • Yellow Fever / complications
  • Yellow Fever / diagnosis
  • Yellow Fever / epidemiology
  • Zika Virus / isolation & purification
  • Zika Virus / physiology
  • Zika Virus Infection / complications
  • Zika Virus Infection / diagnosis
  • Zika Virus Infection / epidemiology