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Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation.
Nat Commun. 2018 Oct 1;9(1):4015. doi: 10.1038/s41467-018-06307-w.
Nat Commun. 2018.
PMID: 30275467
Free PMC article.
A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth.
Lefèvre G, Michel V, Weil D, Lepelletier L, Bizard E, Wolfrum U, Hardelin JP, Petit C.
Lefèvre G, et al.
Development. 2008 Apr;135(8):1427-37. doi: 10.1242/dev.012922. Epub 2008 Mar 13.
Development. 2008.
PMID: 18339676
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Ush1c216A knock-in mouse survives Katrina.
Lentz J, Pan F, Ng SS, Deininger P, Keats B.
Lentz J, et al.
Mutat Res. 2007 Mar 1;616(1-2):139-44. doi: 10.1016/j.mrfmmm.2006.11.006. Epub 2006 Dec 15.
Mutat Res. 2007.
PMID: 17174357
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Ush1c gene expression levels in the ear and eye suggest different roles for Ush1c in neurosensory organs in a new Ush1c knockout mouse.
Tian C, Liu XZ, Han F, Yu H, Longo-Guess C, Yang B, Lu C, Yan D, Zheng QY.
Tian C, et al.
Brain Res. 2010 Apr 30;1328:57-70. doi: 10.1016/j.brainres.2010.02.079. Epub 2010 Mar 6.
Brain Res. 2010.
PMID: 20211154
Free PMC article.
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Harmonin mutations cause mechanotransduction defects in cochlear hair cells.
Grillet N, Xiong W, Reynolds A, Kazmierczak P, Sato T, Lillo C, Dumont RA, Hintermann E, Sczaniecka A, Schwander M, Williams D, Kachar B, Gillespie PG, Müller U.
Grillet N, et al.
Neuron. 2009 May 14;62(3):375-87. doi: 10.1016/j.neuron.2009.04.006.
Neuron. 2009.
PMID: 19447093
Free PMC article.
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