The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania

BMC Res Notes. 2018 Dec 13;11(1):890. doi: 10.1186/s13104-018-3999-9.

Abstract

Objective: The objective of this study was to assess the extent and health burden of neurocysticercosis in the general community of the Mbulu district, northern Tanzania. About 1051 randomly select participants were screened for human cysticercosis. The Cysticercus Western Blot IgG and Computed Tomography scan were used to detect infection by cysticerci. The DALYs was used to assess the community's health burden vis-a-vis neurocysticercosis.

Results: The sero-prevalence of HCC was 16.27%. About 76% of 25 selected human cysticercosis sero-positives had neurocysticercosis suggestive lesions on CT scan and 74% had history of epilepsy. Epilepsy caused 2.8 years of life lost and 2.2 healthy years of life lost due to disability per 1000 person-years in Mbulu. The average DALYs imposed due to neurocysticercosis and epilepsy were 3.0 and 3.9 per 1000 person-years, respectively. Neurocysticercosis is a serious public health concern in northern Tanzania.

Keywords: Human cysticercosis; Mbulu district; Neurocysticercosis; Status.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Cost of Illness*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Middle Aged
  • Neurocysticercosis / blood
  • Neurocysticercosis / diagnostic imaging
  • Neurocysticercosis / epidemiology*
  • Prevalence
  • Seroepidemiologic Studies
  • Tanzania / epidemiology
  • Tomography, X-Ray Computed
  • Young Adult