Primitive Neuroectodermal Tumor in a Child with Human Immunodeficiency Virus Infection: A Rare Association

J Trop Pediatr. 2020 Feb 1;66(1):106-109. doi: 10.1093/tropej/fmz034.

Abstract

Children with human immunodeficiency virus (HIV) infection are reported to have various malignancies, most common being Non-Hodgkin lymphoma. Despite higher risk of malignancies, brain tumors are infrequently described in these children. We report Primitive Neuroectodermal tumor (PNET) in a young boy with HIV infection. PNET has never been described in association with HIV infection. Though a causative association cannot be established, it does emphasize that with longer survivals on effective antiretroviral therapy, we may see a wide range of malignancies more frequently.

Keywords: human immunodeficiency virus infection; malignancy; primitive neuroectodermal tumor; severe immunosuppression.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms / complications*
  • Brain Neoplasms / diagnostic imaging
  • Brain Neoplasms / pathology
  • Child, Preschool
  • Combined Modality Therapy
  • HIV Infections / complications*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Neuroectodermal Tumors, Primitive / complications*
  • Neuroectodermal Tumors, Primitive / diagnostic imaging
  • Neuroectodermal Tumors, Primitive / pathology