IKZF1/3 and CRL4CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma

IKZF1/3 and CRL4^CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma

Haematologica. 2020 May;105(5):e237-e241. doi: 10.3324/haematol.2019.217943. Epub 2019 Sep 26.

¹ Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.
² Comprehensive Cancer Center Mainfranken, University Hospital of Würzburg, Würzburg, Germany.
³ Department of Hematology, Mayo Clinic, Scottsdale, AZ, USA.
⁴ Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany and CCU Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Germany.
⁵ Hematology Department Hospital 12 de Octubre, Complutense University, H12O-CNIO Clinical Research Unit, CIBERONC Madrid, Spain.
⁶ Gene Center, Ludwig-Maximilians University, Munich, Germany.
⁷ Institute of Pathology, University of Würzburg, Würzburg, Germany.
⁸ Center for Individualized Medicine of the Mayo Clinic, Rochester, MN, USA.
⁹ Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany kortuem_m@ukw.de.

No abstract available