Crohn's disease is stated to be an immune-mediated disease initiated by Mycobacterium avium subspecies paratuberculosis (MAP) infection within a period of host immunological vulnerability and induced by the widespread prevalence of that organism in the human food chain. For over two decades, steroids and biologics have, move often than not, been able to induce temporary remissions, but not cures. This thesis examines how the only two, very divergent, therapeutic approaches that have produced cures achieved this positive outcome.
Keywords: Crohn’s disease; Cure; Immune template; Mycobacterium avium subspecies paratuberculosis.
Copyright © 2020 Elsevier Ltd. All rights reserved.