Cathepsin G-Not Only Inflammation: The Immune Protease Can Regulate Normal Physiological Processes

Front Immunol. 2020 Mar 3:11:411. doi: 10.3389/fimmu.2020.00411. eCollection 2020.

Authors

Tatyana S Zamolodchikova¹, Svetlana M Tolpygo¹, Elena V Svirshchevskaya²

Affiliations

¹ Physiology of Motivation Laboratory, P. K. Anokhin Institute of Normal Physiology, Moscow, Russia.
² Immunology Department, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow, Russia.

No abstract available

Keywords: Paneth cells; cathepsin G; duodenal mucosa; homeostasis; inflammation; intestinal glands.

MeSH terms

Angiotensins / metabolism
Cadherins / metabolism
Cathepsin G / physiology*
Crohn Disease / enzymology
Crohn Disease / immunology
Duodenum / enzymology
Enteropeptidase / metabolism
Epithelial Cells / enzymology
Epithelial Cells / metabolism
Humans
Inflammation / enzymology*
Inflammation / immunology
Intestinal Mucosa / enzymology*
Neutrophils / enzymology
Neutrophils / immunology
Paneth Cells / enzymology
Protein Precursors / metabolism
Protein Processing, Post-Translational
Proteolysis
Renin / metabolism

Substances

Angiotensins
Cadherins
Protein Precursors
CTSG protein, human
Cathepsin G
Enteropeptidase
Renin