TranspoScope: interactive visualization of retrotransposon insertions

Bioinformatics. 2020 Jun 1;36(12):3877-3878. doi: 10.1093/bioinformatics/btaa244.

Abstract

Motivation: Retrotransposition is an important force in shaping the human genome and is involved in prenatal development, disease and aging. Current genome browsers are not optimized for visualizing the experimental evidence for retrotransposon insertions.

Results: We have developed a specialized browser to visualize the evidence for retrotransposon insertions for both targeted and whole-genome sequencing data.

Availability and implementation: TranspoScope's source code, as well as installation instructions, are available at https://github.com/FenyoLab/transposcope.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genome, Human
  • Humans
  • Retroelements* / genetics
  • Software*
  • Whole Genome Sequencing

Substances

  • Retroelements