Is there a future for CYP1A2 pharmacogenetics in the optimal dosing of clozapine?

Pharmacogenomics. 2020 Apr;21(6):369-373. doi: 10.2217/pgs-2020-0015. Epub 2020 Apr 20.

Can-Jun Ruan¹, Jose de Leon^{2

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¹ Laboratory of Clinical Psychopharmacology & The National Clinical Research Center for Mental Disorders & Beijing Key Lab of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
² Mental Health Research Center, Eastern State Hospital, Lexington, KY 40511, USA.
³ Psychiatry & Neurosciences Research Group (CTS-549), Institute of Neurosciences, University of Granada, Granada, Spain.
⁴ Biomedical Research Centre in Mental Health Net (CIBERSAM), Santiago Apóstol Hospital, University of the Basque Country, Vitoria, Spain.

No abstract available

Keywords: Asian continental ancestry group/genetics; drug interactions; gene frequency/genetics; inflammation; obesity; phenotype; sex; smoking.

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