Application of nanomaterials in treatment, anti-infection and detection of coronaviruses

Nanomedicine (Lond). 2020 Jun;15(15):1501-1512. doi: 10.2217/nnm-2020-0117. Epub 2020 May 7.

Abstract

Nanotechnology and nanomedicine have excellent potential in dealing with a range of different health problems, including viruses, which are considered to be a serious challenge in the medical field. Application of nanobiotechnology could represent a new avenue for the treatment or disinfection of viruses. There is increasing concern regarding the control of coronaviruses, among these, Middle East respiratory syndrome coronavirus, severe acute respiratory syndrome coronavirus and severe acute respiratory syndrome coronavirus-2 are well known and dangerous examples. This article aims to provide an overview of recent studies on the effectiveness of nanoparticles as diagnostic or antiviral tools against coronaviruses. The possibilities of effectively using nanomaterials as vaccines and nanosensors in this field are also presented.

Keywords: COVID-19; antiviral; bio-labeling; coronaviruses; gold nanoparticles; protein nanoparticles; severe acute respiratory syndrome coronavirus; silver nanoparticles; transmissible gastroenteritis virus; vaccine nanotechnology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antiviral Agents / analysis
  • Antiviral Agents / therapeutic use*
  • Biosensing Techniques / methods
  • COVID-19
  • Coronavirus / drug effects
  • Coronavirus / isolation & purification
  • Coronavirus Infections / diagnosis*
  • Coronavirus Infections / prevention & control
  • Coronavirus Infections / therapy*
  • Humans
  • Nanomedicine / methods
  • Nanoparticles / analysis
  • Nanoparticles / therapeutic use*
  • Nanotechnology / methods
  • Pandemics / prevention & control
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / prevention & control
  • Pneumonia, Viral / therapy

Substances

  • Antiviral Agents