Simultaneous pectus excavatum correction and lung transplantation-A case series

Am J Transplant. 2021 Jan;21(1):410-414. doi: 10.1111/ajt.16180. Epub 2020 Aug 4.

Abstract

Severe chest wall deformities are considered an absolute contraindication for lung transplantation. The significantly impaired chest compliance associated with pectus excavatum is thought to result in a high risk of postoperative respiratory complications and significant morbidity and mortality. We herein report our pooled institutional experience consisting of 3 patients who underwent bilateral lung transplantation and simultaneous correction of a pectus excavatum. Two of the patients were children and 1 patient had severe asymmetric pectus. All patients received a size-reduced double lung transplant and the deformity was corrected by a Nuss or modified Ravitch procedure. The perioperative course was complicated by prolonged weaning requiring tracheostomy in 2 of the 3 patients. However, long-term results were good and all 3 patients are alive in excellent clinical condition 72, 60, and 12 months after the transplantation. This case series demonstrates that patients with severe chest wall deformities should not a priori be excluded from lung transplantation, and a combined approach is feasible for selected patients.

Keywords: clinical research/practice; lung transplantation/pulmonology; patient referral; surgical technique.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Funnel Chest* / surgery
  • Humans
  • Lung Transplantation* / adverse effects
  • Postoperative Complications