Medicinal plants used in wound dressings made of electrospun nanofibers

J Tissue Eng Regen Med. 2020 Nov;14(11):1527-1548. doi: 10.1002/term.3119. Epub 2020 Sep 4.

Abstract

Nanofibers are a type of nanostructures, which due to their unique properties can be used in wound dressing, and electrospinning is a good way to produce them. The benefits of wound dressings made of electrospun nanofibers include a large surface area to volume ratio, high absorption of secretions from the wound, and high air permeability, mimicking the morphology of extracellular matrix (ECM) of the damaged tissue and the possibility of the gradual release of the drug agents loaded on nanofibers. Because of the adaptability of plants to the body, low side effects and the prevalence of antibiotic resistance, interest in using plants is increasing. Combining nanofibers with plants is a way to integrate the physical properties of the structure of nanofibers and the chemical and antibacterial properties of the plants. In recent years, many plants in the forms of extracts, essential oils, and pure active ingredients have been used in the electrospininng and production of nanofiber-containing plants; some of the plants may be a good choice for wound dressings made of electrospun nanofibers.

Keywords: active ingredient; electrospinning; essence; extract; nanofiber; wound dressing.

Publication types

  • Review

MeSH terms

  • Animals
  • Bandages*
  • Humans
  • Nanofibers / chemistry*
  • Plants, Medicinal / chemistry*
  • Tissue Engineering*
  • Wound Healing*