Handheld swept-source optical coherence tomography guided by smartphone-enabled wide-field autofluorescence photography for imaging facial sebaceous glands

Opt Lett. 2020 Oct 15;45(20):5704-5707. doi: 10.1364/OL.405765.

Abstract

We report a method to image facial sebaceous glands (SGs) using smartphone-enabled wide-field autofluorescence photography (AFP) and handheld swept-source optical coherence tomography (SS-OCT). Smartphone-enabled AFP provides a 2D wide-field fluorescence image that is used both as a functional mapping of the sebum and a positioning guidance for OCT imaging of the SG. Following the guidance, handheld SS-OCT conducts the volume scan to investigate depth-resolved conditions of the SG in the selected regions of interest. We show the results from smartphone-enabled AFP and handheld SS-OCT to demonstrate the ability of our method to image facial SGs, potentially useful for the assessment of skin conditions in dermatology and cosmetology.

MeSH terms

  • Face / diagnostic imaging*
  • Fluorescence*
  • Humans
  • Photography*
  • Sebaceous Glands / diagnostic imaging*
  • Smartphone*
  • Tomography, Optical Coherence / instrumentation*