A Case of Hemophagocytic Lymphohistiocytosis Associated With Mediterranean Spotted Fever in a Healthy 29-Year-Old Female

Nour Karra; Rina Dolinski; Luiza Akria; Yevgeni Yampoulski; Jamal Awad

doi:10.1093/ofid/ofaa355

A Case of Hemophagocytic Lymphohistiocytosis Associated With Mediterranean Spotted Fever in a Healthy 29-Year-Old Female

Open Forum Infect Dis. 2020 Aug 13;7(10):ofaa355. doi: 10.1093/ofid/ofaa355. eCollection 2020 Oct.

Authors

Nour Karra¹, Rina Dolinski^{2

3}, Luiza Akria^{3

4}, Yevgeni Yampoulski^{2

3}, Jamal Awad^{2

3}

Affiliations

¹ Internal Medicine Department E, The Chaim Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel.
² Internal Medicine Department F, Galilee Medical Center, Nahariya, Israel.
³ Faculty of Medicine in the Galilee, Bar Ilan University, Safed, Israel.
⁴ Hematology Department, Galilee Medical Center, Nahariya, Israel.

Abstract

A 29-year-old female presented with fever, headache, and epigastric pain. Though her initial presentation was benign and nonspecific, she soon developed a full-blown cytokine storm with disseminated intravascular coagulation. She was diagnosed with hemophagocytosis secondary to Rickettsia conorii infection. A good outcome was achieved thanks to prompt diagnosis and proper treatment.

Keywords: Mediterranean spotted fever; Rickettsia; hemophagocytosis.

Publication types

Case Reports