Chitinase 3-like-1 protects airway function despite promoting type 2 inflammation during fungal-associated allergic airway inflammation

Am J Physiol Lung Cell Mol Physiol. 2021 Apr 1;320(4):L615-L626. doi: 10.1152/ajplung.00528.2020. Epub 2021 Feb 3.

Authors

Affiliations

¹ Department of Medicine, University of Alabama Birmingham, Birmingham, Alabama.
² Department of Microbiology and Immunology, Tulane University, New Orleans, Louisiana.
³ Department of Microbiology, University of Alabama Birmingham, Birmingham, Alabama.
⁴ Department of Medicine, Wake Forest University, Winston-Salem, North Carolina.
⁵ Department of Medicine, University of Arizona, Tucson, Arizona.

No abstract available

Keywords: asthma; fungal; inflammation.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Animals
Aspergillosis / complications*
Aspergillosis / microbiology
Aspergillus fumigatus / physiology
Chitinase-3-Like Protein 1 / physiology*
Female
Inflammation / microbiology
Inflammation / pathology*
Male
Mice
Mice, Inbred BALB C
Mice, Knockout
Respiratory Hypersensitivity / etiology
Respiratory Hypersensitivity / metabolism
Respiratory Hypersensitivity / pathology
Respiratory Hypersensitivity / prevention & control*

Substances

Chil1 protein, mouse
Chitinase-3-Like Protein 1

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