Characterization of the novel HLA-DRB3*03:49 allele by sequencing-based typing

HLA. 2021 May;97(5):477-478. doi: 10.1111/tan.14211. Epub 2021 Feb 18.

Authors

Marine Cargou^{1

2}, Marco Andreani³, Maria Troiano³, Mamy Ralazamahaleo¹, Jonathan Visentin^{1

2}

Affiliations

¹ CHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, Hôpital Pellegrin, Bordeaux, France.
² University of Bordeaux, ImmunoConcEpT, CNRS UMR 5146, Bordeaux, France.
³ Laboratorio d'Immunogenetica dei Trapianti, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy.

PMID: 33565267
DOI: 10.1111/tan.14211

Abstract

HLA-DRB3*03:49 differs from DRB3*03:01:01:01 by one nucleotide substitution in codon 191 in exon 4.

Keywords: HLA-DRB3*03:49; human leukocyte antigen; novel allele; sequencing-based typing.

© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles
Codon
Exons / genetics
HLA-DRB1 Chains / genetics
HLA-DRB3 Chains* / genetics
Histocompatibility Testing
Humans
Sequence Analysis, DNA

Substances

Codon
HLA-DRB1 Chains
HLA-DRB3 Chains