Disorders of the Fourth Cranial Nerve

J Neuroophthalmol. 2021 Jun 1;41(2):176-193. doi: 10.1097/WNO.0000000000001261.

Abstract

This review of disorders of the fourth cranial nerve includes discussion on anatomy, examination techniques, congenital and acquired etiologies, differential diagnosis, and management options. The findings of the superior oblique muscle on orbital MRI in patients with fourth nerve palsy have had a major impact on our understanding of this cranial neuropathy. In addition, briefly reviewed are rare disorders of the fourth nerve: superior oblique myokymia, Brown syndrome, and ocular neuromyotonia. It behooves the clinician to have a clear understanding of the role that the fourth cranial nerve plays in a variety of neuro-ophthalmic conditions.

Publication types

  • Review

MeSH terms

  • Cranial Nerve Diseases / complications
  • Cranial Nerve Diseases / diagnosis*
  • Humans
  • Magnetic Resonance Imaging
  • Ocular Motility Disorders / diagnosis
  • Ocular Motility Disorders / etiology*
  • Oculomotor Muscles / diagnostic imaging
  • Oculomotor Muscles / innervation*
  • Trochlear Nerve / diagnostic imaging*