FNDC4 and FNDC5 reduce SARS-CoV-2 entry points and spike glycoprotein S1-induced pyroptosis, apoptosis, and necroptosis in human adipocytes

Cell Mol Immunol. 2021 Oct;18(10):2457-2459. doi: 10.1038/s41423-021-00762-0. Epub 2021 Aug 31.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipocytes / pathology*
  • Apoptosis
  • COVID-19 / pathology*
  • COVID-19 / virology
  • Fibronectins / metabolism*
  • Humans
  • Necroptosis
  • Obesity / complications*
  • Obesity / pathology
  • Proteins / metabolism*
  • Pyroptosis
  • SARS-CoV-2 / physiology
  • Spike Glycoprotein, Coronavirus

Substances

  • FNDC4 protein, human
  • FNDC5 protein, human
  • Fibronectins
  • Proteins
  • Spike Glycoprotein, Coronavirus
  • spike protein, SARS-CoV-2