LAPTM5 Restricts HIV-1 Infection in Dendritic Cells and Is Counteracted by Vpr

Microbiol Spectr. 2022 Apr 27;10(2):e0138221. doi: 10.1128/spectrum.01382-21. Epub 2022 Feb 28.

Authors

Jiayue Ouyang^{1

2}, Ying Xiong^{1

2}, Hong Shang^{1

2}, Guoxin Liang^{1

3

2}

Affiliations

¹ Key Laboratory of AIDS Immunology of Ministry of Health, Department of Laboratory Medicine, the First Affiliated Hospital, China Medical University, Shenyang, China.
² National Clinical Research Center for Laboratory Medicine, the First Affiliated Hospital of China Medical University, Shenyang, China.
³ Research Institute for Cancer Therapy, the First Affiliated Hospital, China Medical University, Shenyang, China.

No abstract available

Keywords: HIV; LAPTM5; dendritic cells; host restriction factor.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Dendritic Cells
HIV Infections*
HIV-1
Humans
Membrane Proteins*
Virus Replication
vpr Gene Products, Human Immunodeficiency Virus*

Substances

Membrane Proteins
vpr Gene Products, Human Immunodeficiency Virus
vpr protein, Human immunodeficiency virus 1
LAPTM5 protein, human