Sarcoidosis and Its Dermatological Manifestations: A Narrative Review

Cureus. 2022 Aug 16;14(8):e28053. doi: 10.7759/cureus.28053. eCollection 2022 Aug.

Abstract

Sarcoidosis is an enigma diagnosed by ruling out other etiologies of granulomatous inflammation. The multisystem manifestations of sarcoidosis and the clinical polymorphism pose a diagnostic challenge to all physicians. The skin is the most commonly affected organ after the lungs in sarcoidosis. Dermatological manifestations can appear before, during, or after systemic involvement, and the type of skin lesion can have prognostic significance. Also, a biopsy of skin lesions is less invasive and more accessible to perform than a biopsy of visceral organs. Thus, in certain ways, cutaneous manifestations can aid in the diagnosis and prognosis of systemic disease. This article has focused on the frequently encountered skin lesions of sarcoidosis along with their prevalence, clinical features, and management.

Keywords: cutaneous sarcoidosis; erythema nodosum; lupus pernio; sarcoidosis; subcutaneous nodules.

Publication types

  • Review