Huntington's Disease Clinical Trials Corner: November 2022

J Huntingtons Dis. 2022;11(4):351-367. doi: 10.3233/JHD-229006.

Abstract

In this edition of the Huntington's Disease Clinical Trials Corner, we expand on the PIVOT HD (PTC518), and SIGNAL (pepinemab) trials, and list all currently registered and ongoing clinical trials in Huntington's disease.We also introduce a 'breaking news' section highlighting recent updates about the SELECT HD, uniQure AMT-130, and VIBRANT HD clinical trials.

Trial registration: ClinicalTrials.gov NCT05358717 NCT05032196 NCT05111249 NCT05243017 NCT04120493 NCT02481674.

Keywords: Huntington disease; clinical trials.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Clinical Trials as Topic
  • Humans
  • Huntington Disease* / therapy
  • Longitudinal Studies

Substances

  • pepinemab

Associated data

  • ClinicalTrials.gov/NCT05358717
  • ClinicalTrials.gov/NCT05032196
  • ClinicalTrials.gov/NCT05111249
  • ClinicalTrials.gov/NCT05243017
  • ClinicalTrials.gov/NCT04120493
  • ClinicalTrials.gov/NCT02481674