Patients undergoing revisions for total knee replacement malposition are younger and more often female: An analysis of data from the Dutch Arthroplasty register

Background: The proportion of patients who are dissatisfied with the outcome following total knee replacement (TKR) is high. Malalignment is considered a probable cause for persistent pain, but whether this reason for revision could be the result of specific patient characteristics remains unclear. Therefore, we aim to assess whether specific patient characteristics are associated with revision for symptomatic TKR malalignment.

Methods: Data was obtained from the Dutch Arthroplasty Register (LROI), which contains data from all Dutch hospitals. All patients who underwent TKR revision surgery between 2008 and 2019 were included in this study. The (primary) reason for revision as well as patient characteristics (age, gender, ASA classification, and pre-operative patient-reported outcome measures) were abstracted. The Chi-square test for categorical variables, and ANOVA or Kruskal-Wallis for continuous variables were used to determine differences in patient characteristics between the subgroups based on reason for revision.

Results: A total of 11,044 TKR revisions were registered in The Netherlands between 2008 and 2019. Malalignment was registered as the primary reason for revision in 13% of the patients. Subgroup analyses showed that patients who underwent TKR revisions for malalignment where younger (63.8 year, SD ± 9.3) and more often female (70%) compared to other major reasons for TKR revisions.

Conclusion: Patients who had a TKR revision for malalignment were younger and more often female. This suggests that patient characteristics may play a role when reasons to perform revision surgery are considered. Surgeons should invest in the expectation management in (young) patients and inform patients of these potential risk factors as part of shared decision-making.