Inhibition of protein synthesis in vitro by a lectin from Momordica charantia and by other haemagglutinins

Biochem J. 1979 Aug 15;182(2):633-5. doi: 10.1042/bj1820633.

Abstract

Protein synthesis by a rabbit reticulocyte lysate is inhibited by the haemagglutinating lectins from Momordica charantia and Crotalaria juncea seeds and from the roe of Rutilus rutilus, and by a commercial preparation of the mitogenic lectin from Phytolacca americana. The haemagglutinins from the seeds of Ricinus communis and of Vicia cracca acquired inhibitory activity after their reduction with 2-mercaptoethanol.

MeSH terms

  • Cell-Free System
  • Hemagglutinins / pharmacology
  • In Vitro Techniques
  • Lectins / pharmacology*
  • Mercaptoethanol
  • Plant Lectins
  • Protein Biosynthesis*
  • Seeds / analysis

Substances

  • Hemagglutinins
  • Lectins
  • Plant Lectins
  • Mercaptoethanol