Abstract
Light and heavy chain mRNAs of 15 anti-oxazolone antibodies were sequenced directly using synthetic primers. Hybridomas obtained 7 days after primary immunization show that they are of restricted heterogeneity. The majority expressed a single sequence with minor differences concentrated in the D region and joining boundaries D--JH and V kappa--J kappa.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antibodies, Monoclonal / analysis
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Base Sequence
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Immunoglobulin G / genetics
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Immunoglobulin G / immunology*
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Immunoglobulin Idiotypes / immunology
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Mice
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Mice, Inbred BALB C
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Oxazoles / immunology*
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Oxazolone / analogs & derivatives
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Oxazolone / immunology*
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RNA, Messenger / analysis*
Substances
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Antibodies, Monoclonal
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Immunoglobulin G
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Immunoglobulin Idiotypes
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Oxazoles
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RNA, Messenger
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2-phenyloxazolone
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Oxazolone
Associated data
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GENBANK/K00718
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GENBANK/K00719
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GENBANK/K00720
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GENBANK/K00721
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GENBANK/K00722
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GENBANK/K00723
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GENBANK/K00724
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GENBANK/K00725
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GENBANK/K00726
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GENBANK/K00727
-
GENBANK/K00728
-
GENBANK/K00729
-
GENBANK/K00730
-
GENBANK/K00731
-
GENBANK/K00732
-
GENBANK/K00733
-
GENBANK/K00734
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GENBANK/K00735
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GENBANK/K00736
-
GENBANK/K00737
-
GENBANK/K00738
-
GENBANK/K00739
-
GENBANK/K00740
-
GENBANK/K00741
-
GENBANK/K00742
-
GENBANK/K00743
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GENBANK/K00744
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GENBANK/K00745
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GENBANK/K00746
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GENBANK/K00747