Herbimycin B, a new benzoquinonoid ansamycin with anti-TMV and herbicidal activities

J Antibiot (Tokyo). 1980 Oct;33(10):1114-9. doi: 10.7164/antibiotics.33.1114.

Abstract

A new benzoquinonoid ansamycin, herbimycin B was isolated from the culture broth of Streptomyces hygroscopicus No. AM-3672, a herbimycin A-producing strain. Herbimycin B showed potent anti-TMV activity. Herbicidal effect of herbimycin B was less than that of herbimycin A.

MeSH terms

  • Animals
  • Anti-Bacterial Agents / analysis
  • Anti-Bacterial Agents / biosynthesis
  • Anti-Bacterial Agents / pharmacology*
  • Benzoquinones
  • Chemical Phenomena
  • Chemistry, Physical
  • Herbicides*
  • Lactams, Macrocyclic
  • Lethal Dose 50
  • Mice
  • Quinones / analysis
  • Quinones / biosynthesis
  • Quinones / pharmacology
  • Rifabutin / analogs & derivatives
  • Streptomyces / metabolism
  • Tobacco Mosaic Virus / drug effects*

Substances

  • Anti-Bacterial Agents
  • Benzoquinones
  • Herbicides
  • Lactams, Macrocyclic
  • Quinones
  • Rifabutin
  • herbimycin