Abstract
The cellular yes (c-yes) gene is a member of the class of proto-oncogenes that encode non-receptor tyrosine protein kinases. In this report we describe the isolation of cDNAs that encode the murine c-yes gene product and analysis of the nucleotide sequence of the murine c-yes cDNA clones. The reading frame encodes a protein of 541 amino acids with a calculated molecular mass of 60.63 kDa that is reactive with anti-Yes antisera and possesses protein kinase activity.
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Cloning, Molecular*
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DNA / isolation & purification*
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Genes, src
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Mice
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Molecular Sequence Data
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Protein-Tyrosine Kinases / chemistry
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Protein-Tyrosine Kinases / genetics*
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Proto-Oncogene Proteins / chemistry
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Proto-Oncogene Proteins / genetics*
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Proto-Oncogene Proteins c-yes
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Xenopus Proteins
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Xenopus laevis
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src-Family Kinases*
Substances
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Proto-Oncogene Proteins
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Xenopus Proteins
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DNA
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Protein-Tyrosine Kinases
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Proto-Oncogene Proteins c-yes
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YES1 protein, Xenopus
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Yes1 protein, mouse
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src-Family Kinases