Abstract
Keloids, hypertrophic scars, and contractures are a result of aberrations of the normal wound healing process. An understanding of the cellular and molecular events that are implicated in the development of these fibroproliferative disorders will allow for optimization of wound healing. In turn, treatment choices can be based on the most current scientific information available.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Adult
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Child
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Cicatrix, Hypertrophic / etiology
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Cicatrix, Hypertrophic / metabolism
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Cicatrix, Hypertrophic / pathology
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Cicatrix, Hypertrophic / therapy*
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Contracture / etiology
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Contracture / metabolism
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Contracture / pathology
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Contracture / therapy*
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Cytokines / physiology*
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Female
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Fibroblasts / metabolism
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Humans
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Interferons / physiology*
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Keloid / etiology
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Keloid / metabolism
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Keloid / pathology
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Keloid / therapy*
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Lymphoproliferative Disorders / prevention & control
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Male